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When should methotrexate be stopped? Previously it was recommended that men stop methotrexate three months before trying for a baby, but research has now been done that suggests that they may not need to. You should still talk to your healthcare team for advice about trying for a family.
Why do you take methotrexate only once a week? Methotrexate, sold under the brand name Methoblastin, is an antifolate drug, which means it inhibits the activation of folic acid in the body. It is taken once per week to treat a range of conditions. These include rheumatoid arthritis, the skin disorder psoriasis and inflammatory bowel disease.
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