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In: Angaran DM, Whalen KL, eds. Medication Therapy Management: A Comprehensive Approach. New York, NY: McGrawHill; 2015.

When the colon or large intestine gets chronically inflamed, we are said to suffer from ulcerative colitis.

This medication should not be taken by mothers who are breastfeeding, as it increases the risk for a type of jaundice in the newborn (kernicterus) that can cause brain problems in infants younger than two years old.

Current guidelines, therefore, advocate the early and sustained use of DMARDs in RA; methotrexate and sulfasalazine are the most commonly prescribed.

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Smoking cessation benefits patients with CD in relation to their disease course and benefits UC patients from a general health point of view (smoking cessation is associated with flaring of UC).

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Dopamine isnt usually the first treatment choice for heart failure, but it is especially useful in premature babies and infants with other heart problems.

The term scleroderma is taken from the Greek words “skleros” and “derma.

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Their pathobiology remains unknown, and there is little agreement on their diagnostic boundaries.

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Second-line drugs include systemic corticosteroids, leukotriene antagonists, mast cell stabilizer, doxepin, thyroxine, nifedipine, terbutaline, sulfasalazine, and so on.

Crohn's disease patients, especially those with fat malabsorption are susceptible to nephrolithiasis from calcium oxalate stones.

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Exclusive enteral nutrition can settle symptoms in inflammatory disease, especially in children; however, how it affects the inflammation is unknown, since relapse upon stopping enteral nutrition is common unless some other intervention has been undertaken.

Ustekinumab has been reported to be useful in the treatment of the paradoxical effects of anti-TNF therapy.

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Severe periodontal disease and chronic infection of the gums is associated with RA and with developing antibodies to an antigen called cyclic citrullinated peptide (CCP).

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The medical management of Crohn's disease is based on the location and severity of disease and extra-intestinal complications ().

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The Combinatietherapie Bij Reumatoide Artritis (COBRA) trial demonstrated that step-down combination therapy with prednisolone, methotrexate, and sulfasalazine (SSZ) was superior to SSZ monotherapy for suppressing disease activity and radiologic progression of rheumatoid arthritis (RA).

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