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The disorder of the bone have to be considered not only with regard to the bone itself but also with regard to the consequences of disturbed mineral metabolism of extra skeletal sites, including the vasculature.

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Kidney function may become impaired, and metastatic calcifications (calcium deposition in organs throughout the body) may occur, particularly affecting the kidneys.

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Dept of Veterans Affairs for research; Received salary from American Society of Nephrology for asn council position; Received salary from University of Louisville for employment; Received salary from University of Louisville Physicians for employment; Received contract payment from American Physician Institute for Advanced Professional Studies, LLC for independent contractor; Received contract payment from Healthcare Quality Strategies, Inc for independent cont.

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This form of osteoporosis differs from primary osteoporosis and most other forms of secondary osteoporosis because with glucocorticoid-induced osteoporosis inhibition of bone formation is the dominant mechanism for weakening of the skeleton.

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