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Bicalutamide, 50-mg daily, is a logical first choice for antiandrogen therapy when used in combination with an LHRH-A for the treatment of patients with advanced prostate cancer.

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Calutide (50 mg)- Bicalutamide- Tablet is used for Advanced carcinoma of prostate in combination therapy with a lutenizing hormone releasing hormone (LHRH).

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Enzalutamide is an oral androgen-receptor inhibitor that prolongs survival in men with metastatic castration-resistant prostate cancer in whom the disease has progressed after chemotherapy.

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This test uses transrectal ultrasound to measure the size of the prostate gland, and the ratio of prostate gland size to PSA level is calculated.

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The companies are collaborating on a comprehensive development program that includes studies to develop enzalutamide across the full spectrum of advanced prostate cancer as well as advanced breast cancer.

It has been proposed that due to the lower relative effect of NSAAs on sexual interest and activity, with two-thirds of advanced or metastatic prostate cancer patients treated with them retaining sexual interest, these drugs may result in improved and thus be preferable for those who wish to retain sexual interest and function relative to other antiandrogen therapies in prostate cancer.

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Many nonrandomized trials of neoadjuvant androgen deprivation (NAD) therapy have been conducted on patients with clinical stage T1-T3 disease (see Table 2, below).

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