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We thank all the patients who took part in this trial; the members of the data and safety monitoring board, Andrea Apter, Serpil Erzurum, Barbara Layman, Yancy Phillips, Bruce Psaty, and James Sheller; and our study coordinators, Denise Beaver, Kelly Bixler, Jennifer Brandorff, Terry Britton, Peggy Cadbury, Alyson Clayborn, Vanessa Curtis, Mary Gill, Robert Hmieleski, Donna Jinwright, Christena Kolakowski, Jeffrey Krings, Lauren Leshak, Aimee Merchlinski, Barbara Miller, Surinder Narula, Brenda Patterson, Melanie Payton, Jean Schenkkan, Ann Sexton, Kerrie Sheaffer, Allen Stevens, Melissa Thrasher, Suzanne Vogt, Rhonda Webb, Lynda Weichel-Williams, Cheryl Wilmoth, Tiffany Wirth, Muhammad Zahid, Ronald Zimmerman, and Kathy Zheng.

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Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.

I've been on Spiriva my eyes are getting very blurry, (use to get blurry only when I needed to use my inhaler), have gained terrible belly weight, my normal daily bowel habits are now every other day with constipation and gas, I was hospitalized for a blocked small intestine, my breathing hasn't improved much and my sleeping is now intermittent.

Patients should keep an ongoing record of their peak flow readings to help them detect worsening of their condition.

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It was more effective than ipratropium and equal to salmeterol in decreasing COPD exacerbations.

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The committee was less certain about safety, voting 9-4 that the drug has no significant risk of all-cause mortality, despite what one member called a "lingering unease" that there might be an elevated risk of fatal heart attack.

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Adverse event data taken from over 26 clinical trials demonstrated the safety profile consistent with original registration trials.

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All-cause mortality was similar between SPIRIVA HANDIHALER and SPIRIVA RESPIMAT.

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Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trial.

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There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

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The RESPIMAT inhaler locks automatically once the dose indicator has reached the end of the scale.

Instruct patients to be alert for signs and symptoms of urinary retention (e.

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However, if you do need to clean your inhaler, you should open the dust cap and mouthpiece and then press the piercing button to open the base.

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